Conversion to dog years, I pick male that wants Conversion to dog years
How old is your dog in human years?
Our Scotch collie, Buckaroo, is just shy of 14 years old. Now, researchers say they have a new formula see calculator below to convert dog years to human years—one with some actual science behind it.
Scientists have built a case that one such modification, the addition of methyl groups to specific DNA sequences, tracks human biological age—that is, the toll that disease, poor lifestyle, and genetics take on our bodies. Other species also undergo DNA methylation as they age.
Mice, chimpanzees, wolves, and dogs, for example, all seem to have epigenetic clocks. To find out how those clocks differ from the human version, geneticist Trey Ideker of the University of California, San Diego, and colleagues started with dogs. All dogs—no matter the breed—follow a similar developmental trajectory, reaching puberty around 10 months and dying before age They scanned DNA methylation patterns in the genomes of dogs, ranging from 4 weeks to 16 years of age.
Their analysis revealed that dogs at Conversion to dog years Labrador retrievers and humans do have similar age-related methylation of certain genomic regions with high mutation rates; those similarities were most apparent when the scientists looked at young dogs and young humans or old dogs and old humans.
Most importantly, they found that certain groups of genes involved in development are similarly methylated during aging in both species. That suggests at least some aspects of aging are a continuation of development rather than a distinct process—and that at least some of these changes are evolutionarily conserved in mammals, Ideker and colleagues report in a preprint posted online at bioRxiv.
If your dog were a human, it would be:. For example, a 7-week-old puppy would be equivalent roughly to a 9-month-old human baby, both of whom are just starting to sprout teeth. The formula also nicely matches up the average life span of Labrador retrievers 12 years with the worldwide lifetime expectancy of humans 70 years.
Overall, the canine epigentic clock ticks much faster initially than the human one—that 2-year-old Lab may still act like a puppy but it is middle-aged, the methylation-based formula suggests—and then slows down. He hopes to find out why some dogs develop disease at younger ages or die earlier than normal, whereas others live long, disease-free lives.
So, how does our Buckaroo fare?
Happily, the epigenetic clock calculation goes in his favor. By Elizabeth Pennisi Jul. By Warren Cornwall Jul. By Mennatalla Ibrahim Jul. All rights Reserved. A biological clock governs aging in dogs just as in humans.
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